https://appleinsider.com/inside/macos/tips/how-to-get-started-with-wine-80-on-your-mac
..Not all Windows apps will run under Wine, but many do. And Wine helps preserve the ability to run older Windows apps such as Win32-based apps on modern hardware and OS’es…
Since macOS is a POSIX-compliant OS, it is well suited to work with Wine. The 8.0 release of Wine has some interesting improvements including allowing some 32-bit Windows apps to run on 64-bit hardware, and some x86 apps to run on ARM-based machines.
Apple Silicon Macs are supported, including running x86-64 binaries under Rosetta 2…
How to install Wine on your Mac
To install Wine on your Mac, you’ll need to first install XQuartz, either using the installer from the XQuartz site, or via Homebrew in Terminal…There’s a rather hidden direct macOS installer for Wine, but a better way is to use Homebrew to install, since it knows how to install dependencies and knows where everything should be installed…