https://forums.getpaint.net/topic/121643-paintnet-50-is-now-available/
System Requirements
Windows 10 v1809+ or Windows 11
NOTE: Windows 8.1 and Windows 7 SP1 are no longer supported.64-bit CPU and 64-bit version of Windows
Both Intel/AMD x64 and ARM64 are natively supported.
NOTE: 32-bit x86 is no longer supported.